We apply experimental and computational strategies to measure, model, and then therapeutically manipulate cell-to-cell communication, with applications in the development of immune and cancer therapies.
We have openings for well-qualified trainees at the undergraduate, graduate, or postdoctoral levels, specifically on the experimental side of the lab involving the systems analysis of antibody-mediated immunity.
The lab has established an agreement with Merck to profile antibody effector responses across several dimensions. This work should provide a high resolution view of the different design variables that contribute to cell-directed immunity. The approach is modeled by work from the lab to study other receptor families.
Congratulations to Andrew for winning a UCLA EDI Student Leadership Award! This is a campus-wide award recognizing UCLA students who have exhibited exceptional leadership aligning with and contributing to UCLA’s EDI mission and priorities.
Congratulations Jackson on winning a best poster award at the QC Bio retreat! He presented on how tensor methods can be used to find integrative, multi-omic patterns in MRSA infection, which both improves predictions of patient outcomes and helps to interpret the immunology mechanistically.
Ph.D. student Brian Orcutt-Jahns has won another poster award during the Cancer Systems Biology Consortium’s junior investigator meeting. His presentation was on the lab’s approach for designing exceptionally selective cytokines through multivalency.
Congratulations to Marc Creixell for winning a Jonsson Comprehensive Cancer Center predoctoral fellowship! This award will partially support his studies during his final year of studies.
Congratulations to Ph.D. students Farnaz Mohammadi and Cyrillus Tan on winning dissertation year fellowships from UCLA Graduate Division! The dissertation year fellowship will fully support them throughout their final year of studies.
Ph.D. students Marc Creixell and Farnaz Mohammadi will be spending the summer in two industry internships. Marc will be at Calico Life Sciences, using high-throughput proteomics to study immuno-oncology. Farnaz will be at Genentech, using modeling to study drug interaction effects within the cell cycle.
Ph.D. student Jackson Chin presented his work in the UCLA QCBio Research Seminar Series. In it, he showed how coupled matrix-tensor factorization can be used to integrate different molecular determinants of MRSA infection outcome.
Welcome to Michelle Loui! Michelle previously studied biomedical engineering at Arizona State University, performing research on a mix of synthetic biology and biomaterials. She is joining the lab for her Ph.D.