Systems biology: Building better models

We pair experiments with data-driven modeling to learn about cancer biology and innate immune signaling. This combination is necessary and synergistic: models in systems biology are only as good as the information used to assemble them. As our understanding of biology begins to assemble from information about single proteins, we need quantitative models to understand and even communicate these complex processes.


News

The lab has been awarded funding from the NCI Cancer Systems Biology Consortium. This project aims to use systems-level signaling measurements and modeling to determine which lung cancer tumors will respond to AXL inhibitors. The work is in collaboration with the Haura and White labs.

A postdoctoral associate position is available in the Department of Bioengineering at the University of California, Los Angeles (UCLA) to work in the laboratory of Dr. Aaron Meyer. The Meyer lab is an interdisciplinary academic research team that utilizes combined computational and experimental approaches to better understand cancer cell resistance and innate immune signaling. Multiple projects are available within the scope of the lab’s overall focus. A central goal of the lab is to help its members successfully become independent investigators by providing trainees with a supportive environment, close mentorship, and ample resources.

Applicants should hold a Ph.D. degree in Bioengineering, Chemical Engineering, Computational Biology, or related quantitative biological sciences field. Must have experience in the following technical areas: computational methods and tools for analysis, and statistics; and biological experience in one of the following: molecular biology, immunology, or cancer biology. Applicants with exceptionally strong quantitative backgrounds but relatively less experience in biological sciences will be considered. Strong analytical and problem-solving skills are highly valued. Seek a highly motivated, independent individual with excellent documentation skills; strong interpersonal skills; and the ability to contribute in a multidisciplinary team setting, prioritize and perform multiple tasks in a dynamic environment, and execute detailed technical protocols meticulously.

Interested applicants should submit a short cover letter and CV to Dr. Meyer ([email protected]). This should include a short description of the previous project that they are most proud of (science or non-science) and how it reflects the qualities above.

The lab has packed up and moved to the University of California, Los Angeles, in the Department of Bioengineering.

The lab has received funding from the Terri Brodeur Breast Cancer Foundation. This will enable really critical work to study the pleiotropic effects of TAM receptors and develop rationally designed inhibitors. Ultimately, this work aims to also help us determine which patients will benefit from these therapies.

The lab has received funding from the Jayne Koskinas Ted Giovanis Foundation for Health and Policy and the Breast Cancer Research Foundation. This will enable work to study the effects of tumor cell plasticity on drug response and resistance, in collaboration with the Heiser, Peyton, Nie, and Levy labs.

Welcome, Dr. Bae, to the team!

Work from the lab is now out in Cancer Research.

Congrats to Ted and Annelien for winning Koch Institute travel awards!

Research from the Meyer lab has been highlighed on NIH Director Collin’s blog.

Aaron has received the Early Independence Award, a funding mechanism through the NIH Common Fund to allow recent doctoral graduates to rapidly transition to independent research careers.


Contact

Packages/Lab:

Meyer Lab
University of California, Los Angeles
5031 Engineering V
Los Angeles, CA 90095

Mail/Office:

Aaron Meyer
Department of Bioengineering at UCLA
4121G Engineering V
Los Angeles, CA 90095
Phone: (310) 794-4821